General Meeting Agenda (subject to change):

Monday, October 11, 2021 from 11:00am-3:00pm Eastern Time (US) - Times listed below are Eastern Time:

1100 - 1115           Opening Ceremonies: Histiocyte Society President, Michael Jordan; special welcome by Paul Kontoyannis
1115 - 1200           Guest Speaker Presentation: Florent Ginhoux
           "Senescent Langerhans cell histiocytosis cells arise from both dendritic cell (DC) and monocyte/DC3 lineages"
1200 - 1230          Clinical Studies and Registries Update
1230 - 1245        Oral Presentations
Abstract Presentation #1 - Fabrizio De Benedetti
     MACROPHAGE ACTIVATION SYNDROME (MAS) IN SYSTEMIC JUVENILE IDIOPATHIS ARTHRITIS (SJIA): TREATMENT WITH EMAPALUMAB, AN ANTI-INTERFERON GAMMA (IFNγ) ANTIBODY 

Abstract Presentation #2 - Jan-Inge Henter
RESPONSE TO MAP INHIBITION OF NEURODEGENERATION IN LCH MONITORED BY CSF NEUROFILAMENT LIGHT AS A BIOMARKER
1245 - 1300          Break
1300 - 1430          Poster Presentation Session
1430 - 1530+        Virtual Welcome reception via Spatial Chat platform        

Tuesday, October 12, 2021 from 11:00am-3:00pm Eastern Time (US) - Times listed below are Eastern Time:

1100 - 1145           Guest Speaker Presentation: Jana Pachlopnik-Schmid
          "Hemophagocytic lymphohistiocytosis"
1145 - 1315           Abstract presentation Session: Presidential Symposium
      Abstracts nominated for the Nesbit Award in Clinical Science:

THE INTERIM RESULTS OF A MULTICENTER STUDY OF SAFETY AND EFFICACY OF VEMURAFENIB AND CYTARBINE PLUS CLADRIBINE THERAPY IN HIGH-RISK PEDIATRIC LANGERHANS CELL HISTIOCYTOSIS WITH BRAF V600E MUTATION - Dmitry Evseev

PERI-TRANSPLANT ALEMTUZUMAB LEVELS PREDICT RISK OF SECONDARY GRAFT FAILURE AND INVERSELY IMPACT CXCL9 LEVELS AFTER RIC-HCT (A CORRELATIVE BIOLOGY STUDY TO BMT-CTN 1204 RICHI)- Ashley Geerlinks

ALK+ HISTIOCYTOSIS: A NEW CLINICOPATHOLOGIC SPECTRUM HIGHLIGHTING NEUROLOGIC INVOLVEMENT AND RESPONSES TO ALK INHIBITION - Paul Kemps

      Abstracts nominate for the Nezelof Award in Basic Science:

CYTOTOXIC IMPAIRMENT AND EXCESS IL-18 DRIVE SPONTANEOUS, OLIGOCLONAL CD8 T-CELL HYPERACTIVATION AND HYPERINFLAMMATORY DISEASE- Emily Landy

LINEAGE-SWITCH OF CELLS HARBORING BRAF V600E ALLELES IN PATIENTS WITH HIGH RISK LCH TREATED WITH INHIBITORS - Paul Milne

BRAF-V600E EXPRESSION IN DENDRITIC CELLS REPROGRAMS TRANSLATIONAL DYNAMICS TO INCREASE LPS-INDUCED TNFA PRODUCTION - Danielle Minichino
1315 - 1330       Break    
1330 - 1430           General Assembly Business Meeting*
1430 - 1530+         Histiocyte Society ‘Virtual Banquet’ via Spatial Chat and Closing Ceremonies           
      Awarding of Scientific Prizes