Educational Material

Rare Histiocytic Disorders

Clofarabine salvage therapy in refractory multifocal histiocytic disorders, including Langerhans cell histiocytosis, juvenile xanthogranuloma and Rosai-Dorfman disease. Simko SJ, Tran HD, Jones J, Bilgi M, Beaupin LK, Coulter D, Garrington T, McCavit TL, Moore C, Rivera-Ortegón F, Shaffer L, Stork L, Turcotte L, Welsh EC, Hicks MJ, McClain KL, Allen CE. Pediatr Blood Cancer. 2014 Mar;61(3):479-87. doi: 10.1002/pbc.24772. Epub 2013 Sep 18.

Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation. Haroche J, Cohen-Aubart F, Emile JF, Arnaud L, Maksud P, Charlotte F, Cluzel P, Drier A, Hervier B, Benameur N, Besnard S, Donadieu J, Amoura Z. Blood. 2013 Feb 28;121(9):1495-500. doi: 10.1182/blood-2012-07-446286. Epub 2012 Dec 20

Erdheim-Chester Disease / Multifocal Reticulohistiocytosis (MFRH)
Kenneth McClain

Langerhans cell histiocytosis and Erdheim-Chester disease. Wilejto M, Abla O. Curr Opin Rheumatol. 2012 Jan;24(1):90-6. doi: 10.1097/BOR.0b013e32834db53e. Review.

Rosai-Dorfman Disease. Oussama Abla

The Histiocytoses. Ronald Jaffe
Per publisher's request, this is a read-only article and cannot be printed

Juvenile Xanthogranuloma (JXG). Carl Allen; Kenneth McClain

Uncommon histiocytic disorders: the non-Langerhans cell histiocytoses.Weitzman S, Jaffe R.Pediatr Blood Cancer. 2005 Sep;45(3):256-64.

Updates on histiocytic disorders. Vaiselbuh SR, Bryceson YT, Allen CE, Whitlock JA, Abla O. Pediatr Blood Cancer. 2014 Mar 9. doi: 10.1002/pbc.25017.

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